BBBO is one of the most extensively investigated FUS applications, with the safety and efficacy of FUS BBBO having been validated in hundreds of preclinical studies, from rodents to non-human primate models, as well as in both health and disease
Stable cavitation of intravascular microbubbles under FUS induces mechanical forces on the blood–brain barrier (BBB) that transiently increase its permeability for drug delivery
By breaking the immuneprivileged status of the CNS, FUS BBBO could be beneficial for tumour cell detection and initiation of an antitumour immune response.
The appeal of neuromodulation lies in the ability to restore or prevent functional decline by ‘fine-tuning’ the pathological circuits underlying brain disorders.
The solutions of Alzheimer's disease, Parkinson's disease, Traumatic brain injury have been studied
- A study on the diagonsis of demntia through the application of Raman probe.
- A study on the possibility of clinical expansion application after analyzing brain tumors through the application of OCT porbe technology.
- A study on brain tumor treatment that combines Photodynamic therapy and FUS